SIP1 anticorps (N-Term)
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- Antigène Voir toutes SIP1 (GEMIN2) Anticorps
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIP1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- GEMIN2 Antibody detects endogenous levels of total GEMIN2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human GEMIN2, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GEMIN2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- Autre désignation
- GEMIN2 (GEMIN2 Produits)
- Synonymes
- anticorps SIP1, anticorps SIP1-delta, anticorps 1700012N19Rik, anticorps Sip1, anticorps sip1, anticorps sip1-delta, anticorps wu:fc52a05, anticorps zgc:110274, anticorps gem nuclear organelle associated protein 2, anticorps gem (nuclear organelle) associated protein 2, anticorps gem nuclear organelle associated protein 2 S homeolog, anticorps GEMIN2, anticorps Gemin2, anticorps gemin2.S, anticorps gemin2
- Sujet
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Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Gene: GEMIN2
- Poids moléculaire
- 32kDa
- ID gène
- 8487
- UniProt
- O14893
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
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