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PICK1 anticorps (N-Term)

PICK1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6266358
  • Antigène Voir toutes PICK1 Anticorps
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    Épitope
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 31
    • 13
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 5
    • 1
    Lapin
    Clonalité
    • 35
    • 11
    Polyclonal
    Conjugué
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PICK1 est non-conjugé
    Application
    • 33
    • 22
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    PICK1 Antibody detects endogenous levels of total PICK1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PICK1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PICK1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    Autre désignation
    PICK1 (PICK1 Produits)
    Synonymes
    anticorps PICK, anticorps PRKCABP, anticorps Prkcabp, anticorps prkcabp, anticorps MGC131295, anticorps PICK1, anticorps DKFZp470L2127, anticorps protein interacting with PRKCA 1, anticorps protein interacting with C kinase 1, anticorps protein interacting with PRKCA 1 L homeolog, anticorps PICK1, anticorps Pick1, anticorps pick1, anticorps pick1.L
    Sujet

    Description: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

    Gene: PICK1

    Poids moléculaire
    47kDa
    ID gène
    9463
    UniProt
    Q9NRD5
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