Cyclin D2 anticorps
-
- Antigène Voir toutes Cyclin D2 (CCND2) Anticorps
- Cyclin D2 (CCND2)
- Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Cyclin D2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human CCND2
- Isotype
- IgG
- Top Product
- Discover our top product CCND2 Anticorps primaire
-
-
- Indications d'application
-
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200 - Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
-
- Antigène
- Cyclin D2 (CCND2)
- Autre désignation
- CCND2 (CCND2 Produits)
- Synonymes
- anticorps si:ch211-240j22.2, anticorps ccnd2, anticorps CCND2, anticorps kiak0002, anticorps zgc:162280, anticorps LOC100224096, anticorps KIAK0002, anticorps BF642806, anticorps C86853, anticorps Vin-1, anticorps Vin1, anticorps cD2, anticorps 2600016F06Rik, anticorps AI256817, anticorps cyclin D2, b, anticorps cyclin D2 S homeolog, anticorps cyclin D2, anticorps G1/S-specific cyclin-D2, anticorps cyclin D2, a, anticorps cyclin D2 L homeolog, anticorps ccnd2b, anticorps ccnd2.S, anticorps CCND2, anticorps ccnd2, anticorps ccnd2a, anticorps Ccnd2, anticorps ccnd2.L
- Sujet
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3).
- Poids moléculaire
- 33.067 kDa
- ID gène
- 894
- UniProt
- P30279
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
-