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ADGRE2 anticorps

ADGRE2 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6290303
  • Antigène Tous les produits ADGRE2
    ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))
    Reactivité
    Humain, Souris
    Hôte
    • 7
    Lapin
    Clonalité
    • 6
    • 1
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    Cet anticorp ADGRE2 est non-conjugé
    Application
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human EMR2
    Isotype
    IgG
  • Indications d'application
    WB 1:500 - 1:2000
    Commentaires

    Expression is restricted to myeloid cells, Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas, Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested, High expression in mast cells

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène
    ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))
    Autre désignation
    ADGRE2 (ADGRE2 Produits)
    Synonymes
    anticorps CD312, anticorps adhesion G protein-coupled receptor E2, anticorps ADGRE2
    Sujet
    This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Poids moléculaire
    90.472 kDa
    ID gène
    30817
    UniProt
    Q9UHX3
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