CD3 epsilon anticorps (Cytoplasmic Domain)
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- Antigène Voir toutes CD3 epsilon (CD3E) Anticorps
- CD3 epsilon (CD3E)
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Épitope
- AA 156-168, Cytoplasmic Domain
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Reactivité
- Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Cheval, Cobaye
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD3 epsilon est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Fonction
- Mouse anti-Human/Mouse/Rat/Rabbit/Guinea pig/Pig/Horse/Cow CD3e Antibody [Sodium Azide Free]
- Specificité
- Cell surface and cytoplasmic
- Purification
- Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
- Immunogène
- Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
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- Discover our top product CD3E Anticorps primaire
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- Indications d'application
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WB: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- CD3 epsilon (CD3E)
- Autre désignation
- T-cell surface glycoprotein CD3 epsilon chain (CD3E Produits)
- Synonymes
- anticorps cd3e, anticorps CD3E, anticorps t3e, anticorps tcre, anticorps AI504783, anticorps CD3, anticorps CD3epsilon, anticorps T3e, anticorps T3E, anticorps TCRE, anticorps CD3e molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps cd3e, anticorps CD3E, anticorps Cd3e
- Sujet
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Target Description: Recognizes the epsilon chain of CD3, a protein which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Gene Symbol: CD3E///T3E
- ID gène
- 916
- UniProt
- P07766
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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