IGKV1D-16 anticorps

N° du produit ABIN6296345

Détail du produit anti-IGKV1D-16 anticorps

Antigène: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGKV1D-16 est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: Mouse anti-Human Kappa Light Chain Antibody [IHC only]

Specificité: Cell surface, cytoplasmic and secreted

Purification: Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.

Immunogène: Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur IGKV1D-16

Antigène: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Autre désignation: Immunoglobulin kappa variable 1D-16 (IGKV1D-16 Produits)

Synonymes: anticorps IGKV1D16, anticorps L15, anticorps L15a, anticorps immunoglobulin kappa variable 1D-16, anticorps IGKV1D-16

Sujet:

Target Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGKV1D-16///IGKC

ID gène: 3514

UniProt: P01601, P01834