ANO1 anticorps
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- Antigène Voir toutes ANO1 Anticorps
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ANO1 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Fonction
- Mouse anti-Human TMEM16A Antibody (DOG1) [IHC only]
- Specificité
- Cell Surface and Cytoplasmic
- Purification
- Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
- Immunogène
- Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
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- Discover our top product ANO1 Anticorps primaire
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- Indications d'application
- Prediluted format : incubate for 30 min at RT (2)
- Restrictions
- For Research Use only
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- Buffer
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
- Autre désignation
- Anoctamin-1 (ANO1 Produits)
- Synonymes
- anticorps DOG1, anticorps ORAOV2, anticorps TAOS2, anticorps TMEM16A, anticorps Tmem16a, anticorps anoctamin 1, anticorps anoctamin 1, calcium activated chloride channel, anticorps Ano1, anticorps ANO1
- Sujet
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Target Description: Expression of TMEM16A (DOG1) protein is elevated in the gastrointestinal stromal tumors (GIST 's), c-kit signaling-driven mesenchymal tumors of the GI tract. It is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for TMEM16A has been reported in 97.8 percent of scorable GIST 's, including all c-kit negative GIST 's. Overexpression has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha (PDGFR alpha) mutants that fail to express c-kit antigen. The overall sensitivity of TMEM16A and c-kit in GIST 's is nearly identical: 94.4 % vs. 94.7 %.
Gene Symbol: ANO1///DOG1///ORAOV2///TAOS2///TMEM16A
- ID gène
- 55107
- UniProt
- Q5XXA6
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