TYR anticorps
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- Antigène Voir toutes TYR Anticorps
- TYR (Tyrosinase (TYR))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TYR est non-conjugé
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Application
- Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Fonction
- Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]
- Specificité
- Cytoplasmic
- Purification
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
- Immunogène
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
- Top Product
- Discover our top product TYR Anticorps primaire
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- Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- TYR (Tyrosinase (TYR))
- Autre désignation
- Tyrosinase (TYR Produits)
- Synonymes
- anticorps sandy, anticorps zgc:109705, anticorps TYR, anticorps TYRO, anticorps tyr, anticorps LOC100136546, anticorps CMM8, anticorps OCA1A, anticorps OCAIA, anticorps SHEP3, anticorps albino, anticorps c, anticorps skc35, anticorps C, anticorps tyrosinase, anticorps TYRosinase, anticorps tyrosinase S homeolog, anticorps tyr, anticorps tyr-5, anticorps tyr.S, anticorps TYR, anticorps Celal_3121, anticorps Halhy_4121, anticorps Mesop_2736, anticorps LOC100136546, anticorps Tyr
- Sujet
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Target Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.
Gene Symbol: TYR
- ID gène
- 7299
- UniProt
- P14679
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