CD46 anticorps
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- Antigène Voir toutes CD46 Anticorps
- CD46
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Reactivité
- Humain, Babouin
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD46 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Fonction
- Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]
- Specificité
- Cell surface
- Purification
- Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
- Immunogène
- Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
- Top Product
- Discover our top product CD46 Anticorps primaire
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- Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- CD46
- Autre désignation
- Membrane cofactor protein (CD46 Produits)
- Synonymes
- anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
- Sujet
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Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
Gene Symbol: CD46///MCP///MIC10
- ID gène
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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