PAWR anticorps
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- Antigène Voir toutes PAWR Anticorps
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAWR est non-conjugé
- Application
- Veuillez nous consulter SVP
- Fonction
- Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
- Top Product
- Discover our top product PAWR Anticorps primaire
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- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Antigène
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- Autre désignation
- Prostate Apoptosis Response protein-4 (PAWR Produits)
- Synonymes
- anticorps MGC81382, anticorps pawrl, anticorps zgc:103513, anticorps PAWR, anticorps PAR4, anticorps Par-4, anticorps Par4, anticorps 2310001G03Rik, anticorps pro-apoptotic WT1 regulator, anticorps PRKC, apoptosis, WT1, regulator L homeolog, anticorps PRKC, apoptosis, WT1, regulator, anticorps PAWR, anticorps pawr.L, anticorps pawr, anticorps Pawr
- Sujet
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Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Gene Symbol: PAWR
- ID gène
- 5074
- UniProt
- Q96IZ0
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