KCNN3 anticorps (C-Term)

N° du produit ABIN633755

Détail du produit anti-KCNN3 anticorps

Antigène: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNN3 est non-conjugé

Application: Western Blotting (WB)

Specificité: KCNN3 antibody was raised against the C terminal of KCNN3

Purification: Affinity purified

Immunogène: KCNN3 antibody was raised using the C terminal of KCNN3 corresponding to a region with amino acids ITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSA

Information d'application

Indications d'application: WB: 2 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

KCNN3 Blocking Peptide, catalog no. 33R-4172, is also available for use as a blocking control in assays to test for specificity of this KCNN3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNN3 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur KCNN3

Antigène: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Autre désignation: KCNN3 (KCNN3 Produits)

Synonymes: anticorps KCa2.3, anticorps SK3, anticorps SKCA3, anticorps hSK3, anticorps potassium calcium-activated channel subfamily N member 3, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, anticorps Kcnn3, anticorps KCNN3

Sujet: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

Poids moléculaire: 81 kDa (MW of target protein)