FLASH anticorps (N-Term)

N° du produit ABIN636211

Détail du produit anti-FLASH anticorps

Antigène: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Épitope: N-Term

Reactivité: Mammifères

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLASH est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogène: FLASH antibody was raised in rabbit using N terminus of the FLASH protein as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur FLASH

Antigène: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Autre désignation: FLASH (CASP8AP2 Produits)

Synonymes: anticorps CASP8AP2, anticorps FLASH, anticorps fc74h10, anticorps wu:fc74h10, anticorps zgc:113449, anticorps CED-4, anticorps RIP25, anticorps AA387232, anticorps D4Ertd659e, anticorps mKIAA1315, anticorps caspase 8 associated protein 2, anticorps CASP8AP2, anticorps casp8ap2, anticorps Casp8ap2

Sujet: FLASH, contains a motif with oligomerizing activity whose sequence is similar to that of the Caenorhabditis elegans protein CED-4, and another domain (DRD domain) that interacts with a death-effector domain in caspase-8 or in the adapter protein. FLASH is likely a component of the DISC signalling complex and is necessary for the activation of caspase-8 in Fas-mediated apoptosis.

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity