MIA anticorps

N° du produit ABIN636661

Détail du produit anti-MIA anticorps

Antigène: MIA (Melanoma Inhibitory Activity (MIA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA est non-conjugé

Application: ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)

Purification: Purified

Immunogène: MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur MIA

Antigène: MIA (Melanoma Inhibitory Activity (MIA))

Autre désignation: MIA (MIA Produits)

Synonymes: anticorps CD-RAP, anticorps Mia1, anticorps Cdrap, anticorps zgc:194157, anticorps mia, anticorps CDRAP, anticorps Fdp, anticorps MIA, anticorps MIAL, anticorps melanoma inhibitory activity, anticorps otoraplin, anticorps cilia and flagella associated protein 100, anticorps MIA, anticorps Mia, anticorps mia, anticorps Otor, anticorps CFAP100

Sujet: MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

Poids moléculaire: 12.2 kDa (predicted detection band MW)