MIA anticorps

N° du produit ABIN636661

Détail du produit anti-MIA anticorps

Antigène: MIA (Melanoma Inhibitory Activity (MIA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA est non-conjugé

Application: ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)

Purification: Purified

Immunogène: MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur MIA

Antigène: MIA (Melanoma Inhibitory Activity (MIA))

Autre désignation: MIA (MIA Produits)

Sujet: MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

Poids moléculaire: 12.2 kDa (predicted detection band MW)