AGE anticorps

N° du produit ABIN636761

Détail du produit anti-AGE anticorps

Antigène: AGE (Advanced Glycation End Products (AGE))

Reactivité: Veuillez nous consulter SVP

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp AGE est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.

Information d'application

Indications d'application: ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur AGE

Antigène: AGE (Advanced Glycation End Products (AGE))

Autre désignation: AGE (AGE Produits)

Synonymes: anticorps RBP, anticorps RNBP, anticorps renin binding protein, anticorps RENBP

Classe de substances: Chemical

Sujet: Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).