USP33 anticorps

N° du produit ABIN636996

Détail du produit anti-USP33 anticorps

Antigène: USP33 (Ubiquitin Specific Peptidase 33 (USP33))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP33 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogène: USP33 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Information d'application

Indications d'application: IHC-P: 5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Détails sur USP33

Antigène: USP33 (Ubiquitin Specific Peptidase 33 (USP33))

Autre désignation: USP33 (USP33 Produits)

Synonymes: anticorps USP33, anticorps VDU1, anticorps 9830169D19Rik, anticorps AA409780, anticorps Vdu1, anticorps zgc:77308, anticorps ubiquitin specific peptidase 33, anticorps universal stress protein UspA, anticorps Usp33, anticorps USP33, anticorps RR_RS17870, anticorps usp33

Sujet: USP 33 is a deubiquitinating enzyme involved in various processes such as cellular migration and beta-2 adrenergicreceptor/ADRB2 recycling. It is involved in cell migration via its interaction with intracellular domain of ROBO1, leadingto regulation of Slit signaling. It also plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-proteincoupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2adrenergic receptor (ADRB2).

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling