SPEG anticorps

N° du produit ABIN6389343

Détail du produit anti-SPEG anticorps

Antigène: SPEG (SPEG Complex Locus (SPEG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPEG est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Unconjugated Rabbit polyclonal to SPEG

Specificité: SPEG Polyclonal Antibody detects endogenous levels of protein.

Purification: SPEG antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Information d'application

Indications d'application: IHC-p 1:50-300

Commentaires:

Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur SPEG

Antigène: SPEG (SPEG Complex Locus (SPEG))

Autre désignation: SPEG (SPEG Produits)

Poids moléculaire: 359 kDa

ID gène: 10290

UniProt: Q15772