Transportin 1 anticorps (N-Term)

N° du produit ABIN650673

Détail du produit anti-Transportin 1 anticorps

Antigène: Transportin 1 (TNPO1)

Épitope: AA 47-74, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.

Clone: RB17873

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Transportin 1 (ABIN650673)

Conde-Rubio, Mylonas, Widmann: "The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases." dans: Cell death discovery, Vol. 7, Issue 1, pp. 164, (2021) (PubMed).

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: TNPO1 (TNPO1 Produits)

Synonymes: anticorps IPO2, anticorps KPNB2, anticorps MIP, anticorps MIP1, anticorps TRN, anticorps TNPO1, anticorps AU021749, anticorps D13Ertd688e, anticorps Kpnb2, anticorps ATTRN1, anticorps F12A24.13, anticorps F12A24_13, anticorps TRANSPORTIN 1, anticorps transportin 1, anticorps DKFZp469O204, anticorps transportin 1, anticorps transportin-1, anticorps transportin 1 S homeolog, anticorps TNPO1, anticorps LOC738932, anticorps tnpo1, anticorps Tnpo1, anticorps tnpo1.S, anticorps TRN1

Sujet: TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

Poids moléculaire: 102355

ID gène: 3842

NCBI Accession: NP_002261, NP_694858

UniProt: Q92973

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events