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MCAM anticorps (C-Term)

Name: MCAM anticorps (C-Term)
SKU: ABIN650721
Price: 445.5 EUR
Availability: InStock

MCAM Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB20607 unconjugated

Western blot analysis of MC Antibody (C-term) (ABIN650721 and ABIN2839393) in cell line lysates (35 μg/lane). (MCAM anticorps (C-Term))

MC Antibody (C-term) (ABIN650721 and ABIN2839393) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (MCAM anticorps (C-Term))

IHC (p)

2 images

N° du produit ABIN650721

Fiche de données

Antigène Voir toutes MCAM Anticorps

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Épitope
16

12

10

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 532-558, C-Term
Reactivité
133

53

47

14

14

9

8

7

6

2
Humain
Hôte
94

63

8

1

1
Lapin
Anticorps secondaires appropriés
Clonalité
87

80
Polyclonal
Conjugué
70

14

14

11

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MCAM est non-conjugé
Application
85

80

69

43

22

20

13

10

10

5

4

4

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of human MCAM.

Clone

RB20607

Isotype

Ig Fraction

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Indications d'application

WB: 1:1000. IHC-P: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Antigène

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation

MCAM (MCAM Produits)

Synonymes

anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet

MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Poids moléculaire

71607

ID gène

4162

NCBI Accession

NP_006491

UniProt

P43121