MCAM anticorps (AA 161-189)
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- Antigène Voir toutes MCAM Anticorps
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Épitope
- AA 161-189
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MCAM est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human MCAM.
- Clone
- RB20606
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MCAM Anticorps primaire
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- Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Autre désignation
- MCAM (MCAM Produits)
- Synonymes
- anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb
- Sujet
- MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
- Poids moléculaire
- 71607
- ID gène
- 4162
- NCBI Accession
- NP_006491
- UniProt
- P43121
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