GADD45A anticorps (C-Term)

N° du produit ABIN650724

Détail du produit anti-GADD45A anticorps

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Épitope: AA 133-165, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: B, Ha, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This GADD45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the C-terminal region of human GADD45A.

Clone: RB16521

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GADD45A (ABIN650724)

Wu, Boonmars, Nagano, Boonjaraspinyo, Srinontong, Ratasuwan, Narong, Nielsen, Maekawa: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." dans: International journal of cancer. Journal international du cancer, (2015) (PubMed).

Détails sur GADD45A

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Autre désignation: GADD45A (GADD45A Produits)

Synonymes: anticorps MGC53491, anticorps zgc:91795, anticorps gadd45a, anticorps GADD45A, anticorps ddit1, anticorps gadd45, anticorps GADD45, anticorps AA545191, anticorps Ddit1, anticorps DDIT1, anticorps Gadd45, anticorps growth arrest and DNA damage inducible alpha L homeolog, anticorps growth arrest and DNA-damage-inducible, alpha, b, anticorps growth arrest and DNA damage inducible alpha, anticorps growth arrest and DNA damage-inducible protein 45, anticorps growth arrest and DNA-damage-inducible 45 alpha, anticorps growth arrest and DNA-damage-inducible, alpha, anticorps gadd45a.L, anticorps gadd45ab, anticorps GADD45A, anticorps gadd45a, anticorps GADD45, anticorps Gadd45a

Sujet: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.

Poids moléculaire: 18336

ID gène: 1647

NCBI Accession: NP_001186670, NP_001186671, NP_001915

UniProt: P24522

Pathways: Signalisation p53, Cycle Cellulaire