SRSF2 anticorps (AA 76-105)

N° du produit ABIN650729

Détail du produit anti-SRSF2 anticorps

Antigène: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Épitope: AA 76-105

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRSF2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, C, M, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SFRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human SFRS2.

Clone: RB17330

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur SRSF2

Antigène: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Autre désignation: SFRS2 (SRSF2 Produits)

Synonymes: anticorps PR264, anticorps SC-35, anticorps SC35, anticorps SFRS2, anticorps SFRS2A, anticorps SRp30b, anticorps D11Wsu175e, anticorps MRF-1, anticorps Pr264, anticorps Sfrs10, anticorps Sfrs2, anticorps pr264, anticorps sc-35, anticorps sc35, anticorps sfrs2, anticorps sfrs2a, anticorps srp30b, anticorps serine and arginine rich splicing factor 2, anticorps serine/arginine-rich splicing factor 2, anticorps serine/arginine-rich splicing factor 2 L homeolog, anticorps SRSF2, anticorps Srsf2, anticorps srsf2.L

Sujet: SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.

Poids moléculaire: 25476

ID gène: 6427

NCBI Accession: NP_001182356, NP_003007

UniProt: Q01130