NAT8 anticorps (AA 110-138)

N° du produit ABIN651148

Détail du produit anti-NAT8 anticorps

Antigène: NAT8 (N-Acetyltransferase 8 (NAT8))

Épitope: AA 110-138

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAT8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NAT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-138 amino acids from the Central region of human NAT8.

Clone: RB25556

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-NAT8 (ABIN651148)

Ding, Dellisanti, Ko, Czajkowski, Puglielli: "The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides." dans: The Journal of biological chemistry, Vol. 289, Issue 46, pp. 32044-55, (2014) (PubMed).

Ding, Ko, Pehar, Kotch, Peters, Luo, Salamat, Puglielli: "Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation." dans: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 8424-33, (2012) (PubMed).

Détails sur NAT8

Antigène: NAT8 (N-Acetyltransferase 8 (NAT8))

Autre désignation: NAT8 (NAT8 Produits)

Synonymes: anticorps Cml4, anticorps ATase2, anticorps CML1, anticorps GLA, anticorps Hcml1, anticorps TSC501, anticorps TSC510, anticorps 0610037O16Rik, anticorps N-acetyltransferase 8, anticorps N-acetyltransferase 8 (putative), anticorps N-acetyltransferase 8 (GCN5-related), anticorps Nat8, anticorps NAT8

Sujet: This protein, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene.

Poids moléculaire: 25619

ID gène: 9027

NCBI Accession: NP_003951

UniProt: Q9UHE5