ATF6B anticorps (C-Term)

N° du produit ABIN651294

Détail du produit anti-ATF6B anticorps

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Épitope: AA 560-589, C-Term

Reactivité: Humain, Souris, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.

Clone: RB25603

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ATF6B (ABIN651294)

So, Chen, Wang, Wu, Huang, Lai, Pan, Kang, Huang: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." dans: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: CREBL1 (ATF6B Produits)

Synonymes: anticorps CREBL1, anticorps CREB-RP, anticorps G13, anticorps AA617266, anticorps ATF6beta, anticorps Creb-rp, anticorps Crebl1, anticorps activating transcription factor 6 beta, anticorps cyclic AMP-dependent transcription factor ATF-6 beta, anticorps ATF6B, anticorps LOC745411, anticorps Atf6b

Sujet: CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Poids moléculaire: 76709

ID gène: 1388

NCBI Accession: NP_001129625, NP_004372

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction