FOXP2 anticorps (AA 657-684)

N° du produit ABIN651939

Détail du produit anti-FOXP2 anticorps

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Épitope: AA 657-684

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids of human FOXP2.

Clone: RB21207

Isotype: IgG

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-FOXP2 (ABIN651939)

Vibulyaseck, Fujita, Luo, Tran, Oh-Nishi, Ono, Hirano, Sugihara: "Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum." dans: The Journal of comparative neurology, Vol. 525, Issue 14, pp. 2971-2990, (2018) (PubMed).

Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

Détails sur FOXP2

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Autre désignation: FOXP2 (FOXP2 Produits)

Synonymes: anticorps CAGH44, anticorps SPCH1, anticorps TNRC10, anticorps 2810043D05Rik, anticorps AI449000, anticorps CAG-16, anticorps D0Kist7, anticorps RGD1559697, anticorps FOXP2, anticorps spch1, anticorps cagh44, anticorps tnrc10, anticorps xlFoxP2, anticorps foxP2, anticorps foxP, anticorps Foxp2, anticorps foxP2b, anticorps foxp2a, anticorps forkhead box P2, anticorps lmw-gs, anticorps forkhead box transcription factor, anticorps forkhead box P2 L homeolog, anticorps FOXP2, anticorps Foxp2, anticorps foxp2, anticorps foxP2, anticorps foxp1c, anticorps foxp2.L

Sujet: FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Poids moléculaire: 79919

ID gène: 93986

NCBI Accession: NP_001166237, NP_001166238, NP_055306, NP_683696, NP_683697, NP_683698

UniProt: O15409