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KIR2DS2 anticorps (AA 39-65)

KIR2DS2 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB26424 unconjugated
N° du produit ABIN651951
  • Antigène Voir toutes KIR2DS2 Anticorps
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    Épitope
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 39-65
    Reactivité
    Humain
    Hôte
    • 26
    Lapin
    Clonalité
    • 26
    Polyclonal
    Conjugué
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    Cet anticorp KIR2DS2 est non-conjugé
    Application
    • 21
    • 17
    • 16
    • 9
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KIR2DS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human KIR2DS2.
    Clone
    RB26424
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KIR2DS2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    Autre désignation
    KIR2DS2 (KIR2DS2 Produits)
    Synonymes
    anticorps 183ActI, anticorps CD158J, anticorps CD158b, anticorps NKAT5, anticorps cl-49, anticorps killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2, anticorps KIR2DS2
    Sujet
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Poids moléculaire
    33502
    ID gène
    100132285
    NCBI Accession
    NP_036444
    UniProt
    P43631
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