ARHGEF3 anticorps (AA 211-240)

N° du produit ABIN652003

Détail du produit anti-ARHGEF3 anticorps

Antigène: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Épitope: AA 211-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.

Clone: RB27451

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ARHGEF3 (ABIN652003)

Liu, Zheng, Cai, Guo, Lin, Chen, Liao, Kung, Zeng, Xie: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." dans: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).

Détails sur ARHGEF3

Antigène: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Autre désignation: ARHGEF3 (ARHGEF3 Produits)

Synonymes: anticorps MGC82822, anticorps ARHGEF3, anticorps si:ch211-258l4.8, anticorps MGC108040, anticorps DKFZp459N027, anticorps GEF3, anticorps STA3, anticorps XPLN, anticorps 1200004I24Rik, anticorps 9830169H03Rik, anticorps C76747, anticorps Xpln, anticorps Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog, anticorps Rho guanine nucleotide exchange factor 3, anticorps Rho guanine nucleotide exchange factor (GEF) 3, anticorps Rho guanine nucleotide exchange factor (GEF) 3, gene 1, anticorps arhgef3.1.S, anticorps ARHGEF3, anticorps arhgef3, anticorps arhgef3.1, anticorps Arhgef3

Sujet: Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 59783

ID gène: 50650

NCBI Accession: NP_001122087, NP_001122088, NP_062455

UniProt: Q9NR81

Pathways: Neurotrophin Signaling Pathway