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MLF1 anticorps (C-Term)

MLF1 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB18643 unconjugated
N° du produit ABIN652233
  • Antigène Voir toutes MLF1 Anticorps
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Épitope
    • 13
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 215-244, C-Term
    Reactivité
    • 72
    • 45
    • 20
    • 1
    • 1
    Humain, Souris
    Hôte
    • 69
    • 5
    Lapin
    Clonalité
    • 71
    • 3
    Polyclonal
    Conjugué
    • 39
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MLF1 est non-conjugé
    Application
    • 60
    • 28
    • 25
    • 18
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human MLF1.
    Clone
    RB18643
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MLF1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Autre désignation
    MLF1 (MLF1 Produits)
    Synonymes
    anticorps MLF1, anticorps HLS7, anticorps myeloid leukemia factor 1, anticorps myeloid leukemia factor 1 L homeolog, anticorps MLF1, anticorps mlf1.L, anticorps mlf1, anticorps Mlf1
    Sujet
    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
    Poids moléculaire
    30627
    ID gène
    4291
    NCBI Accession
    NP_001123628, NP_001123629, NP_001182361, NP_001182362, NP_001182363, NP_071888
    UniProt
    P58340
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