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PLA2G4A anticorps (AA 513-541)

PLA2G4A Reactivité: Humain WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB21320 unconjugated
N° du produit ABIN652449
  • Antigène Voir toutes PLA2G4A Anticorps
    PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
    Épitope
    • 28
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 513-541
    Reactivité
    • 58
    • 32
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 66
    • 5
    • 2
    • 1
    Lapin
    Clonalité
    • 70
    • 4
    Polyclonal
    Conjugué
    • 41
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLA2G4A est non-conjugé
    Application
    • 60
    • 34
    • 20
    • 14
    • 14
    • 14
    • 10
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    C, Zf, Hs, M, Rb, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.
    Clone
    RB21320
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PLA2G4A Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
    Autre désignation
    PLA2G4A (PLA2G4A Produits)
    Synonymes
    anticorps PLA2G4, anticorps cPLA2-alpha, anticorps Pla2c, anticorps Pla2g4, anticorps cPLA2, anticorps pla2g4, anticorps CPLA2, anticorps PLA2G4A, anticorps PLA2, anticorps PLA2G1B, anticorps cPLA2alpha, anticorps pla2g4a, anticorps si:dkey-97o5.1, anticorps phospholipase A2 group IVA, anticorps phospholipase A2 group IVA L homeolog, anticorps phospholipase A2, group IVA (cytosolic, calcium-dependent), anticorps phospholipase A2, group IVAb (cytosolic, calcium-dependent), anticorps PLA2G4A, anticorps Pla2g4a, anticorps pla2g4a.L, anticorps pla2g4ab
    Sujet
    PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
    Poids moléculaire
    85239
    ID gène
    5321
    NCBI Accession
    NP_077734
    UniProt
    P47712
    Pathways
    Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
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