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ADRA2B anticorps (AA 343-369)

ADRA2B Reactivité: Humain WB, IF, FACS, IHC (p) Hôte: Lapin Polyclonal RB22486 unconjugated
N° du produit ABIN652506
  • Antigène Voir toutes ADRA2B Anticorps
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Épitope
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 343-369
    Reactivité
    • 22
    • 5
    • 4
    Humain
    Hôte
    • 22
    • 2
    • 1
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADRA2B est non-conjugé
    Application
    • 16
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ADRA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-369 amino acids from the Central region of human ADRA2B.
    Clone
    RB22486
    Isotype
    IgG
  • Indications d'application
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Autre désignation
    ADRA2B (ADRA2B Produits)
    Synonymes
    anticorps ADRA2L1, anticorps ADRA2RL1, anticorps ADRARL1, anticorps ALPHA2BAR, anticorps alpha-2BAR, anticorps Adra-2b, anticorps [a]2B, anticorps alpha2-C2, anticorps alpha2B, anticorps ADRA2B, anticorps zgc:194747, anticorps Adra2b, anticorps adrenoceptor alpha 2B, anticorps adrenergic receptor, alpha 2b, anticorps adrenergic, alpha-2B-, receptor, anticorps adrenoceptor alpha 2C, anticorps ADRA2B, anticorps Adra2b, anticorps ADRA2C, anticorps adra2b
    Sujet
    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
    Poids moléculaire
    49954
    ID gène
    151
    NCBI Accession
    NP_000673
    UniProt
    P18089
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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