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SREBF chaperone anticorps (AA 604-632)

SCAP Reactivité: Humain, Souris, Rat WB, IHC (p), FACS, IF Hôte: Lapin Polyclonal RB22508 unconjugated
N° du produit ABIN652508
  • Antigène Voir toutes SREBF chaperone (SCAP) Anticorps
    SREBF chaperone (SCAP)
    Épitope
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 604-632
    Reactivité
    • 27
    • 17
    • 16
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 2
    Lapin
    Clonalité
    • 40
    • 2
    Polyclonal
    Conjugué
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SREBF chaperone est non-conjugé
    Application
    • 33
    • 13
    • 13
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)
    Homologie
    B, Pig
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP.
    Clone
    RB22508
    Isotype
    Ig Fraction
  • Indications d'application
    IF: 1:100. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Takashima, Saitoh, Funabashi, Hirose, Yagi, Nozaki, Sato, Shin, Nakayama: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." dans: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).

  • Antigène
    SREBF chaperone (SCAP)
    Autre désignation
    SCAP (SCAP Produits)
    Synonymes
    anticorps 9530044G19, anticorps mKIAA0199, anticorps SREBF chaperone, anticorps SREBF chaperone S homeolog, anticorps SCAP, anticorps Scap, anticorps scap.S
    Sujet
    SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
    Poids moléculaire
    139729
    ID gène
    22937
    NCBI Accession
    NP_036367
    UniProt
    Q12770
    Pathways
    SARS-CoV-2 Protein Interactome
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