SREBF chaperone anticorps (AA 604-632)

N° du produit ABIN652508

Détail du produit anti-SREBF chaperone anticorps

Antigène: SREBF chaperone (SCAP)

Épitope: AA 604-632

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SREBF chaperone est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Homologie: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP.

Clone: RB22508

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:100. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SREBF chaperone (ABIN652508)

Takashima, Saitoh, Funabashi, Hirose, Yagi, Nozaki, Sato, Shin, Nakayama: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." dans: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).

Détails sur SREBF chaperone

Antigène: SREBF chaperone (SCAP)

Autre désignation: SCAP (SCAP Produits)

Synonymes: anticorps 9530044G19, anticorps mKIAA0199, anticorps SREBF chaperone, anticorps SREBF chaperone S homeolog, anticorps SCAP, anticorps Scap, anticorps scap.S

Sujet: SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Poids moléculaire: 139729

ID gène: 22937

NCBI Accession: NP_036367

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome