C5 anticorps (N-Term)

N° du produit ABIN652518

Détail du produit anti-C5 anticorps

Antigène: C5 (Complement Component 5 (C5))

Épitope: AA 253-281, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Specificité: This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260~289 amino acids from the N-terminal region of human C5.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 AA from the N-terminal region of human C5.

Clone: RB21866

Isotype: IgG

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-C5 (ABIN652518)

Zhang, Huang, Jing, Fu, Yuan, Xia, Cai, Gan, Chen, Zou, Long, Wang, Wang, Xu: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." dans: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: C5 (C5 Produits)

Synonymes: anticorps C5, anticorps LOC565774, anticorps C5a, anticorps C5b, anticorps CPAMD4, anticorps Hc, anticorps RGD1561905, anticorps He, anticorps complement C5, anticorps complement component 5, anticorps hemolytic complement, anticorps C5, anticorps c5, anticorps Hc

Sujet: C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Synonyms: Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, CPAMD4, C5

Poids moléculaire: 188305 DA

ID gène: 727

UniProt: P01031

Pathways: Système du Complément, Carbohydrate Homeostasis