GDNF anticorps (N-Term)
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- Antigène Voir toutes GDNF Anticorps
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Épitope
- AA 8-36, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GDNF est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This GDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human GDNF.
- Clone
- RB21995
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GDNF Anticorps primaire
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- Indications d'application
- IHC-P: 1:10~50. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Autre désignation
- GDNF (GDNF Produits)
- Synonymes
- anticorps gdnf, anticorps GDNF, anticorps AI385739, anticorps gdnfa, anticorps hfb1-gdnf, anticorps ATF1, anticorps ATF2, anticorps HFB1-GDNF, anticorps HSCR3, anticorps glial cell derived neurotrophic factor, anticorps glial cell derived neurotrophic factor a, anticorps glial cell line derived neurotrophic factor, anticorps glial cell derived neurotrophic factor L homeolog, anticorps Gdnf, anticorps gdnfa, anticorps GDNF, anticorps gdnf.L
- Sujet
- GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described.
- Poids moléculaire
- 23720
- ID gène
- 2668
- NCBI Accession
- NP_000505, NP_001177397, NP_001177398, NP_001265027, NP_954701
- UniProt
- P39905
- Pathways
- Signalisation RTK, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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