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SREBF1 anticorps (AA 349-378)
SREBF1
Reactivité: Humain
WB, IHC (p), FACS
Hôte: Lapin
Polyclonal
RB21265
unconjugated
Détail du produit anti-SREBF1 anticorps
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Antigène
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SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
Épitope
Tous les épitopes à travers SREBF1 Anticorps.
AA 349-378
Reactivité
Toutes les réactivités sur SREBF1 Anticorps
Humain
Hôte
Toutes les hôtes sur SREBF1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SREBF1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SREBF1 Anticorps
Cet anticorp SREBF1 est non-conjugé
Application
Tous les applications à travers SREBF1 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Homologie
Ha, M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SREBF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-378 amino acids of human SREBF1.
Clone
RB21265
Isotype
IgG
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Information d'application
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Indications d'application
WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Détails sur SREBF1
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Antigène
SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
Autre désignation
SREBF1 (SREBF1 Produits )
Synonymes
anticorps SREBP-1c, anticorps SREBP1, anticorps bHLHd1, anticorps ADD-1, anticorps ADD1, anticorps D630008H06, anticorps SREBP-1, anticorps SREBP-1a, anticorps SREBP1c, anticorps Srebp1, anticorps SCREBP1, anticorps SREBP-1C, anticorps SREBF1, anticorps srebp1, anticorps sterol regulatory element binding transcription factor 1, anticorps sterol regulatory element binding transcription factor 1 L homeolog, anticorps sterol regulatory element binding protein-1, anticorps Sterol regulatory element Binding Protein, anticorps SREBF1, anticorps Srebf1, anticorps srebf1.L, anticorps SREBP-1, anticorps srebf1, anticorps sbp-1
Sujet
SREBF1 is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family.
Poids moléculaire
121675
ID gène
6720
NCBI Accession
NP_001005291 , NP_004167
UniProt
P36956
Pathways
AMPK Signaling , Caspase Cascade in Apoptosis , Negative Regulation of Hormone Secretion , Regulation of Lipid Metabolism by PPARalpha
Vus récemment
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