Integrin alpha 1 anticorps (AA 727-755)

N° du produit ABIN652761

Détail du produit anti-Integrin alpha 1 anticorps

Antigène: Integrin alpha 1 (ITGA1)

Épitope: AA 727-755

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin alpha 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ITGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1.

Clone: RB23364

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Integrin alpha 1 (ABIN652761)

Gutiérrez-Franco, Costa, Eixarch, Castillo, Medina-Rodríguez, Bribián, de Castro, Montalban, Espejo: "Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design." dans: Clinical immunology (Orlando, Fla.), Vol. 163, pp. 22-33, (2016) (PubMed).

Détails sur Integrin alpha 1

Antigène: Integrin alpha 1 (ITGA1)

Autre désignation: ITGA1 (ITGA1 Produits)

Synonymes: anticorps CD49A, anticorps E130012M19Rik, anticorps Vla1, anticorps CD49a, anticorps VLA1, anticorps integrin alpha 1, anticorps integrin subunit alpha 1, anticorps Itga1, anticorps ITGA1

Sujet: ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.

Poids moléculaire: 130848

ID gène: 3672

NCBI Accession: NP_852478

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex