UNC13B anticorps (AA 1062-1091)

N° du produit ABIN652852

Détail du produit anti-UNC13B anticorps

Antigène: UNC13B (Unc-13 Homolog B (UNC13B))

Épitope: AA 1062-1091

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.

Clone: RB22476

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-UNC13B (ABIN652852)

Kasmapour, Gronow, Bleck, Hong, Gutierrez: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, (2012) (PubMed).

Détails sur UNC13B

Antigène: UNC13B (Unc-13 Homolog B (UNC13B))

Autre désignation: UNC13B (UNC13B Produits)

Synonymes: anticorps MUNC13, anticorps UNC13, anticorps Unc13h2, anticorps UNC13B, anticorps Munc13-2, anticorps Munc13-1, anticorps Unc13a, anticorps Unc13h1, anticorps unc-13 homolog B, anticorps unc-13 homolog B (C. elegans), anticorps UNC13B, anticorps Unc13b

Sujet: UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

Poids moléculaire: 180679

ID gène: 10497

NCBI Accession: NP_006368

UniProt: O14795

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis