NKX3-1 anticorps (AA 118-145)

N° du produit ABIN652945

Détail du produit anti-NKX3-1 anticorps

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Épitope: AA 118-145

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NKX3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human NKX3-1.

Clone: RB23610

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3-1 (NKX3-1 Produits)

Synonymes: anticorps Xbagpipe, anticorps Xbap, anticorps bagpipe, anticorps koza, anticorps nkx3-1, anticorps nkx3.1, anticorps si:ch211-67o1.2, anticorps nkx3a, anticorps MGC53041, anticorps MGC97890, anticorps Bax, anticorps NKX3.1, anticorps NKX3A, anticorps Nkx-3.1, anticorps BAPX2, anticorps NKX3, anticorps NK3 homeobox 1 L homeolog, anticorps NK3 homeobox 1, anticorps NK-3 transcription factor, locus 1 (Drosophila), anticorps nkx3-1.L, anticorps NKX3-1, anticorps nkx3-1, anticorps Nkx3-1

Sujet: NKX3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Poids moléculaire: 26350

ID gène: 4824

NCBI Accession: NP_001243268, NP_006158

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus