FBLN3 anticorps (N-Term)

N° du produit ABIN653039

Détail du produit anti-FBLN3 anticorps

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Épitope: AA 119-148, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBLN3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pr, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EFEMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the N-terminal region of human EFEMP1.

Clone: RB22140

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-FBLN3 (ABIN653039)

Wang, Cao, Huang, Ke, Luo, Lin, Wang, Zhang, Wang: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." dans: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).

Lin, Wang, Zhu, Li, Xie, Xiang: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).

Hu, Gao, Vo, Ke, Pan, Yu, Siegel, Hess, Linskey, Zhou: "Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis." dans: Oncoscience, Vol. 1, Issue 3, pp. 205-15, (2015) (PubMed).

Détails sur FBLN3

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Autre désignation: EFEMP1 (FBLN3 Produits)

Synonymes: anticorps DHRD, anticorps DRAD, anticorps FBLN3, anticorps FBNL, anticorps FIBL-3, anticorps MLVT, anticorps MTLV, anticorps S1-5, anticorps T16, anticorps EGF containing fibulin like extracellular matrix protein 1, anticorps EGF-containing fibulin-like extracellular matrix protein 1, anticorps epidermal growth factor-containing fibulin-like extracellular matrix protein 1, anticorps EFEMP1, anticorps Efemp1

Sujet: EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.

Poids moléculaire: 54641

ID gène: 2202

NCBI Accession: NP_001034437, NP_001034438

UniProt: Q12805

Pathways: EGFR Signaling Pathway