HMGA1 anticorps (C-Term)

N° du produit ABIN653050

Détail du produit anti-HMGA1 anticorps

Antigène: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Épitope: AA 64-93, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Homologie: Ha, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HMGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the C-terminal region of human HMGA1.

Clone: RB17645

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HMGA1 (ABIN653050)

Liu, Zhang, Li, Ding, Tu, Zhou, Qi, Chen, Sun: "Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1." dans: International journal of oncology, Vol. 46, Issue 6, pp. 2526-34, (2015) (PubMed).

Détails sur HMGA1

Antigène: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Autre désignation: HMGA1 (HMGA1 Produits)

Sujet: HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

Poids moléculaire: 11676

ID gène: 3159

NCBI Accession: NP_002122, NP_665906, NP_665908, NP_665909, NP_665910, NP_665912

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagy