IL-10 anticorps (AA 27-53)
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- Antigène Voir toutes IL-10 (IL10) Anticorps
- IL-10 (IL10) (Interleukin 10 (IL10))
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Épitope
- AA 27-53
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-10 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- EBV, Pr
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from the Central region of human IL10.
- Clone
- RB21234
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IL10 Anticorps primaire
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- Indications d'application
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- IL-10 (IL10) (Interleukin 10 (IL10))
- Autre désignation
- IL10 (IL10 Produits)
- Sujet
- The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
- Poids moléculaire
- 20517
- ID gène
- 3586
- NCBI Accession
- NP_000563
- UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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