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GSTa2 anticorps (N-Term)

GSTa2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB24006 unconjugated
N° du produit ABIN653362
  • Antigène Voir toutes GSTa2 Anticorps
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Épitope
    • 14
    • 8
    • 7
    • 2
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 38
    • 3
    • 1
    Humain
    Hôte
    • 35
    • 4
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GSTa2 est non-conjugé
    Application
    • 32
    • 24
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This GSTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GSTA2.
    Clone
    RB24006
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GSTa2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." dans: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

    Li, Yuan, Li, Liu, Hua, Lu, Zhang: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." dans: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).

  • Antigène
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Autre désignation
    GSTA2 (GSTa2 Produits)
    Synonymes
    anticorps GSTA1, anticorps GST2, anticorps GSTA2-2, anticorps GTA2, anticorps GTH2, anticorps Gsta1, anticorps Gst2-2, anticorps Gstc-2, anticorps Gstc2, anticorps glutathione S-transferase alpha 2, anticorps glutathione S-transferase, anticorps glutathione S-transferase, alpha 2 (Yc2), anticorps GSTA2, anticorps Gsta2
    Sujet
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
    Poids moléculaire
    25664
    ID gène
    2939
    NCBI Accession
    NP_000837
    UniProt
    P09210
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