Hepcidin anticorps (AA 17-46)

N° du produit ABIN653413

Détail du produit anti-Hepcidin anticorps

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Épitope: AA 17-46

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HAMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the Central region of human HAMP.

Clone: RB22098

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: HAMP (HAMP Produits)

Synonymes: anticorps HEPC, anticorps HFE2B, anticorps LEAP1, anticorps PLTR, anticorps Hepcidin, anticorps Hamp1, anticorps Hepc, anticorps Hepc1, anticorps HAMP, anticorps hepcidin, anticorps hamp1, anticorps hep1, anticorps hepcidin antimicrobial peptide, anticorps hepcidin-like, anticorps hepcidin-1, anticorps Ham percentage, anticorps HAMP, anticorps Hamp, anticorps hamp, anticorps LOC100135935, anticorps LOC106584587

Sujet: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Poids moléculaire: 9408

ID gène: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis