CHMP4B anticorps (N-Term)
-
- Antigène Voir toutes CHMP4B Anticorps
- CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
-
Épitope
- AA 51-79, N-Term
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CHMP4B est non-conjugé
-
Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- C, Zf, M, X
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.
- Clone
- RB24088
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CHMP4B Anticorps primaire
-
-
- Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
-
-
High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." dans: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).
: "
-
High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." dans: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).
-
- Antigène
- CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
- Autre désignation
- CHMP4B (CHMP4B Produits)
- Sujet
- CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
- Poids moléculaire
- 24950
- ID gène
- 128866
- NCBI Accession
- NP_789782
- UniProt
- Q9H444
-