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CHMP4B anticorps (N-Term)

CHMP4B Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB24088 unconjugated
N° du produit ABIN653481
  • Antigène Voir toutes CHMP4B Anticorps
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Épitope
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-79, N-Term
    Reactivité
    • 39
    • 22
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 38
    • 1
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHMP4B est non-conjugé
    Application
    • 14
    • 14
    • 13
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, Zf, M, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.
    Clone
    RB24088
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CHMP4B Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." dans: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).

  • Antigène
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Autre désignation
    CHMP4B (CHMP4B Produits)
    Sujet
    CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
    Poids moléculaire
    24950
    ID gène
    128866
    NCBI Accession
    NP_789782
    UniProt
    Q9H444
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