AANAT anticorps (N-Term)

N° du produit ABIN653578

Détail du produit anti-AANAT anticorps

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Épitope: AA 27-54, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AANAT est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT.

Clone: RB23834

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur AANAT

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Autre désignation: AANAT (AANAT Produits)

Synonymes: anticorps DSPS, anticorps SNAT, anticorps AA-NAT, anticorps Nat4, anticorps Nat-2, anticorps Snat, anticorps aralkylamine N-acetyltransferase, anticorps arylalkylamine N-acetyltransferase, anticorps AANAT, anticorps Aanat

Sujet: AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

Poids moléculaire: 23344

ID gène: 15

NCBI Accession: NP_001079, NP_001160051

UniProt: Q16613

Pathways: Photoperiodism