This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This NEIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human NEIL1.
anticorps FPG1, anticorps NEI1, anticorps hFPG1, anticorps 2810450N13Rik, anticorps Nei1, anticorps nei-like DNA glycosylase 1, anticorps nei like DNA glycosylase 1, anticorps nei endonuclease VIII-like 1 (E. coli), anticorps Neil1, anticorps NEIL1
Sujet
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).