This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This FCRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-507 amino acids from the C-terminal region of human FCRL4.
anticorps CD307d, anticorps FCRH4, anticorps IGFP2, anticorps IRTA1, anticorps FCRL4, anticorps Fc receptor like 4, anticorps Fc receptor-like 4, anticorps Fc receptor-like 4 L homeolog, anticorps FCRL4, anticorps fcrl4, anticorps fcrl4.L
Sujet
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.