MAP4K3 anticorps

N° du produit ABIN653817

Détail du produit anti-MAP4K3 anticorps

Antigène: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP4K3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAP4K3 antibody is generated from rabbits immunized with a recombinant protein of human MAP4K3.

Clone: RB22192

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MAP4K3

Antigène: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Autre désignation: MAP4K3 (MAP4K3 Produits)

Synonymes: anticorps GLK, anticorps MAPKKKK3, anticorps MEKKK 3, anticorps MEKKK3, anticorps RAB8IPL1, anticorps 4833416M01Rik, anticorps 4833416M07Rik, anticorps 9530052P13Rik, anticorps Glk, anticorps mitogen-activated protein kinase kinase kinase kinase 3, anticorps MAP4K3, anticorps Map4k3

Sujet: MAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

Poids moléculaire: 101316

ID gène: 8491

NCBI Accession: NP_001257354, NP_003609

UniProt: Q8IVH8

Pathways: Signalisation MAPK