WASP anticorps (AA 116-144)

N° du produit ABIN653830

Détail du produit anti-WASP anticorps

Antigène: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Épitope: AA 116-144

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WASP est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human WAS.

Clone: RB23643

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur WASP

Antigène: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Autre désignation: WAS (WAS Produits)

Synonymes: anticorps IMD2, anticorps SCNX, anticorps THC, anticorps THC1, anticorps WASP, anticorps U42471, anticorps WASp, anticorps Wasp, anticorps imd2, anticorps thc, anticorps thc1, anticorps was, anticorps wasp, anticorps wu:fk81c08, anticorps zgc:64164, anticorps Wiskott-Aldrich syndrome, anticorps neural Wiskott-Aldrich syndrome protein, anticorps wiskott-aldrich syndrome protein, anticorps Wiskott-Aldrich syndrome L homeolog, anticorps Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b, anticorps WAS, anticorps LOC5578888, anticorps CpipJ_CPIJ006699, anticorps Was, anticorps was.L, anticorps wasb

Sujet: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients.

Poids moléculaire: 52913

ID gène: 7454

NCBI Accession: NP_000368

UniProt: P42768