This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GTSE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human GTSE1.
anticorps gtse1, anticorps MGC81588, anticorps MGC89498, anticorps GTSE1, anticorps fb70b04, anticorps fj88g09, anticorps wu:fb70b04, anticorps wu:fj88g09, anticorps wu:fy65d12, anticorps MGC114722, anticorps B99, anticorps Gtse-1, anticorps RGD1563164, anticorps G2 and S-phase expressed 1 S homeolog, anticorps G2 and S-phase expressed 1, anticorps G-2 and S-phase expressed 1, anticorps G2 and S-phase expressed 1 L homeolog, anticorps G two S phase expressed protein 1, anticorps gtse1.S, anticorps gtse1, anticorps GTSE1, anticorps gtse1.L, anticorps Gtse1
Sujet
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.