MARCO anticorps (AA 13-40)

N° du produit ABIN653847

Détail du produit anti-MARCO anticorps

Antigène: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Épitope: AA 13-40

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCO est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.

Clone: RB24662

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MARCO (ABIN653847)

Ohta, Moriyama, Maehara, Gion, Furukawa, Tanaka, Hayashida, Yamauchi, Ishiguro, Mikami, Tsuboi, Iizuka-Koga, Kawano, Sato, Kiyoshima, Sumida, Nakamura: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." dans: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).

Chao, Makale, Karmali, Sharikov, Tsigelny, Merkulov, Kesari, Wrasidlo, Ruoslahti, Simberg: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." dans: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).

Détails sur MARCO

Antigène: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Autre désignation: MARCO (MARCO Produits)

Synonymes: anticorps AI323439, anticorps Ly112, anticorps Scara2, anticorps SCARA2, anticorps macrophage receptor with collagenous structure, anticorps MARCO, anticorps Marco

Sujet: MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Poids moléculaire: 52658

ID gène: 8685

NCBI Accession: NP_006761

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response