Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 511-539) anticorps

N° du produit ABIN654100

Détail du produit

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Épitope: AA 511-539

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCDHGC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the Central region of human PCDHGC3.

Clone: RB22247

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Autre désignation: PCDHGC3 (PCDHGC3 Produits)

Synonymes: anticorps PC43, anticorps PCDH-GAMMA-C3, anticorps PCDH2, anticorps Pcdh2, anticorps PCDHGA11, anticorps PCDHGC5, anticorps protocadherin gamma subfamily C, 3, anticorps PCDHGC3, anticorps Pcdhgc3

Sujet: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Poids moléculaire: 101077

ID gène: 5098

NCBI Accession: NP_002579, NP_115778

UniProt: Q9UN70